The Reds host Wolves knowing three points could hand them the Premier League title, permitting Brighton can stop Manchester City from winning at the Amex Stadium.
Jurgen Klopp and his side will still have the Champions League final to look forward to whatever happens today, which will soften the blow should they fall short.
But this will definitely be their last match at Anfield this season so supporters can expect to see some final goodbyes this afternoon.
After the game, the squad will do a lap of honour with their families to thank fans for their support across the course of the campaign.
The players will just be hoping they have a special reason to celebrate.
With a number of players out of contract this summer and a host of others linked with moves away, which players could be saying farewell this afternoon?
Alberto Moreno is another player who is on his way. He fell out of favour after Andy Robertson replaced him in the side in December 2017 and the Scotsman simply hasn’t looked back.
James Milner is out of contract too, which seems ludicrous given the huge part he played in their historic comeback against Barcelona in midweek.
There is still optimism that he can extend for a further year, but that may hinge on whether boyhood club Leeds get promoted back to the top-flight.
Rafael Camacho has been one of the shining lights in the PL2 this season and he could be on his way out of the club this summer.
According to reports in Spain, Real Madrid are eyeing a shock move for the Portuguese midfielder.
Simon Mignolet has shown a first class attitude this season as Alisson’s understudy and Klopp has praised the impact he has had in the dressing room and around Melwood.
It’s likely he will sit down with the manager at the end of the season and ask to leave so that he can play regularly again, so this could be farewell.
Those five players will be hoping to sign off in style and as Premier League champions.
Milner is the only one almost guaranteed to play a part today, with Sturridge potentially coming off the bench.
First and foremost Klopp will only care about the result but should they be leading Wolves comfortably, he may try and get them some minutes to receive an ovation from the Kop.