Liverpool will need Brighton to do them a favour by taking points off Manchester City at the Amex, but all the Reds can do is win and hope.
Jurgen Klopp will have to get his players refocused after the ecstasy of their incredible Champions League comeback against Barcelona.
They will want to ensure they finish their Premier League season on a high at Anfield.
Wolves have now secured seventh place but have proven time and time again this season that they can take points off the top six.
They beat the Reds 2-1 back in January in the FA Cup but lost their league encounter at Molineux 2-0 in December.
Klopp confirmed on Friday that Andy Robertson should be fit to face Wolves.
The left-back was forced off at half-time against Barcelona with a calf problem, following a clash with Luis Suarez.
It’s unlikely the German will risk Robertson if there’s any uncertainty and therefore it’s likely James Milner gets the nod as a precaution.
Jordan Henderson is also expected to be available after he soldiered on with the help of an injection in midweek.
Mohamed Salah took part in Liverpool training on Friday as he looks to return from a head injury sustained at Newcastle.
The Egyptian is expected to make his return to the side as he looks to retain the Premier League Golden Boot.
Salah is currently two goals clear (with 22) of Sergio Aguero, Pierre-Emerick Aubameyang and Sadio Mane (all on 20).
Divock Origi is likely to keep his place after playing his part on Tuesday with two goals that will go down in the history books.
Roberto Firmino will not be available for the clash.
The Brazilian suffered a muscle problem last month and aggravated it when he returned too soon at the Camp Nou.
Klopp is optimistic he will be ready for action for the Champions League at the Wanda Metropolitano on June 1.
Liverpool predicted line-up vs Wolves: Alisson; Alexander-Arnold, Van Dijk, Matip, Milner; Fabinho, Wijnaldum, Henderson; Mane, Salah, Origi.